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CCG 2979
CAS No. 328070-87-7
CCG 2979( CCG2979 )
Catalog No. M14070 CAS No. 328070-87-7
CCG 2979 is a small molecule inhibitor of gene expression of streptokinase (SK), a critical group A streptococcal (GAS) virulence factor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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Biological Information
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Product NameCCG 2979
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NoteResearch use only, not for human use.
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Brief DescriptionCCG 2979 is a small molecule inhibitor of gene expression of streptokinase (SK), a critical group A streptococcal (GAS) virulence factor.
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DescriptionCCG 2979 is a small molecule inhibitor of gene expression of streptokinase (SK), a critical group A streptococcal (GAS) virulence factor; inhibits expression of SK by 60% at 50 uM based on activity assay, also inhibits the production of active SK protein; enhances granulocyte phagocytosis and killing of GAS in an in vitro assay, also protecteds mice from GAS-induced mortality in vivo.
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In Vitro——
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In Vivo——
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SynonymsCCG2979
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number328070-87-7
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Formula Weight394.577
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Molecular FormulaC24H30N2OS
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCSC1=NC2=C(C(=O)N1CC=C)C3(CCCCC3)CC4=CC=CC=C42
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Chemical Name2-butylsulfanyl-3-prop-2-enylspiro[6H-benzo[h]quinazoline-5,1'-cyclohexane]-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sun H, et al. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3469-74.
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